SYLLABUS

Differential scan calorimetry (DSC)

Determination of melting point of suppository bases and suppositories
Determination of glass transition temperature of polymers and the effect of plasticization
Evaluation of solid dispersions by DSC

Pycnometric density of solids, porosimetry

Determination of tablet´s excipients density
Determination of tableting materials density
Determination of density and porosity of tablets in dependence on compression pressure

 Determination of surface tension of liquids

Determination of surface tension of water
Determination of surface tension of surfactant solutions (cationic, anionic and nonionic)

 Rheological evaluation of pharmaceutical preparations

Analysis of rheogram by appropriate models
Characterization of  semi-solid preparations by Herschel-Bulkely model (coefficient of consistency and flow behaviour)
Thixotropy characterization of the pharmaceutical preparations
Influence of the pharmaceutical preparations composition and technology of compounding on rheological characteristics

Spray drying

Influence of process parameters on the quality of a dried product
Evaluation of the spray dried product

 Evaluation of the compressibility of tabletting materials and the effect of lubricants. 3D printing of tablets.

Evaluation of the energetic profile of dry binders and directly compressible tabletting materials
Evaluation of the compactibility of dry binders and directly compressible tabletting materials by tensile strength of tablets
Evaluation of the lubricant effect in tabletting materials
Selective laser sintering as a method of tablet preparation

 Dissolution tests

Determination of active ingredients dissolution profile released from prolonged release tablets
Comparison of basket, paddle and flow- through cell dissolution methods
Influence of dissolution test´s settings on dissolution profiles