Osnova sekce

  • Differential scan calorimetry (DSC) (Eva Šnejdrová)

    Determination of melting point of suppository bases and suppositories
    Determination of glass transition temperature of polymers and the effect of plasticization
    Evaluation of solid dispersions by DSC

    Pycnometric density of solids, porosimetry, laser diffraction (Monika Smékalová)

    Determination of tablet´s excipients density
    Determination of tablet´s excipients porosity
    Determination of particle size by laser diffraction

     Determination of surface tension of liquids (Monika Smékalová)

    Determination of surface tension of water
    Determination of surface tension of surfactant solutions (cationic, anionic and nonionic)

    Rheological evaluation of pharmaceutical preparations (Eva Šnejdrová)

    Analysis of rheogram by appropriate models
    Characterization of  semi-solid preparations by Herschel-Bulkely model (coefficient of consistency and flow behaviour)
    Thixotropy characterization of the pharmaceutical preparations
    Influence of the pharmaceutical preparations composition and technology of compounding on rheological characteristics

    Spray drying (Petra Svačinová)

    Influence of process parameters on the quality of a dried product
    Evaluation of the spray dried product

    Evaluation of the compressibility of tabletting materials and the effect of lubricants. (Jitka Mužíková)

    Evaluation of the energy profile of  compression of dry binders and their mixtures with lubricants
    Evaluation of the compactability and lubricant sensitivity of dry binders 
    Evaluation of the lubricant effect in tabletting materials

     Dissolution tests (Pavel Ondrejček)

    Determination of active ingredients dissolution profile released from prolonged release tablets
    Comparison of basket, paddle and flow- through cell dissolution methods
    Influence of dissolution test´s settings on dissolution profiles