Course: Pharmaceutical Technology II - Practical Training

Section outline

Select section INTRODUCTION

INTRODUCTION

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- Select activity Oznámení
  
  Oznámení Forum
- Select activity Dear students, wellcome in the interactive ...
  
  Dear students,
  
  wellcome in the interactive Moodle course from Pharmaceutical Technology II. supplementing the practical training. The course you are in will, not only serve as study material for practical exercises but will also test your knowledge of the covered topics.
  
  Each topic contains the interactive contents that are designed to repeat your knowledge that you gained at the practical training and by studying the theoretical background.
  
  Your teachers from Department of Pharmaceutical Technology
- Select activity __________________________________________________...
  
  ___________________________________________________________________________________
  
  COURSE CONTENT:
- Select activity 1. Preparation and evaluation of granular powders ...
  
  1. Preparation and evaluation of granular powders
  
  2. Evaluation of flow properties, preparation of microparticles, sugar coating
  
  3. Dissolution testing
  
  4. Properties of tablets
  
  5. Rheology
- Select activity Oznámení
  
  Oznámení Forum
Select section PREPARATION AND EVALUATION OF GRANULAR POWDERS

PREPARATION AND EVALUATION OF GRANULAR POWDERS
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  PRACTICAL TRAINING:
- Select activity Video: Granular powder preparation
  
  Video: Granular powder preparation Interactive Content
- Select activity Video: Determination of the moisture content
  
  Video: Determination of the moisture content Interactive Content
- Select activity Video: Determination of the mechanical resistance of granular powder
  
  Video: Determination of the mechanical resistance of granular powder Interactive Content
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  EXAMPLE OF THE PROTOCOL:
- Select activity Protocol: Sieve test, mechanical resistance of granules, moisture content
  
  Protocol: Sieve test, mechanical resistance of granules, moisture content File
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  ADDITIONAL MATERIALS:
- Select activity Youtube video: Principle of sieve analysis
  
  Youtube video: Principle of sieve analysis Interactive Content
- Select activity Youtube video: Sieve analysis
  
  Youtube video: Sieve analysis Interactive Content
- Select activity European Phamacopoeia: Granules
  
  European Phamacopoeia: Granules File
- Select activity European Pharmacopoeia: Particle-size distribution estimation by analytical sieving
  
  European Pharmacopoeia: Particle-size distribution estimation by analytical sieving File
- Select activity European Pharmacopoeia: Friability of granules and spheroids
  
  European Pharmacopoeia: Friability of granules and spheroids File
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  TASKS
- Select activity Task No. 1: Granular powder preparation, properties
  
  Task No. 1: Granular powder preparation, properties Assignment
Select section EVALUATION OF FLOW PROPERTIES, PREPARATION OF MICROPARTICLES, SUGAR COATING

EVALUATION OF FLOW PROPERTIES, PREPARATION OF MICROPARTICLES, SUGAR COATING
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  PRACTICAL TRAINING:
- Select activity Video: Angle of repose, flow through an orifice
  
  Video: Angle of repose, flow through an orifice Interactive Content
- Select activity Angle of repose
  
  Angle of repose Interactive Content
- Select activity Angle of repose - powder with poor flow properties
  
  Angle of repose - powder with poor flow properties Journal
- Select activity Video: Determination of the tapped volume/density
  
  Video: Determination of the tapped volume/density Interactive Content
- Select activity Hausner ratio and compressibility index - granular powder
  
  Hausner ratio and compressibility index - granular powder Interactive Content
- Select activity Hausner ratio and compressibility index - lactose
  
  Hausner ratio and compressibility index - lactose Interactive Content
- Select activity Hausner ratio and compressibility index - potato starch
  
  Hausner ratio and compressibility index - potato starch Interactive Content
- Select activity Video: Preparation of microparticles
  
  Video: Preparation of microparticles Interactive Content
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  EXAMPLE OF THE PROTOCOL:
- Select activity Protocol: Flow properties, Hausner ratio, compressibility index
  
  Protocol: Flow properties, Hausner ratio, compressibility index File
- Select activity Protocol: Microparticles
  
  Protocol: Microparticles File
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  ADDITIONAL MATERIALS:
- Select activity Youtube video: Shear cell
  
  Youtube video: Shear cell Interactive Content
- Select activity Youtube video: Sugar coating
  
  Youtube video: Sugar coating Interactive Content
- Select activity European Pharmacopoeia: Bulk density and tapped density of powders
  
  European Pharmacopoeia: Bulk density and tapped density of powders File
- Select activity European Pharmacopoeia: Flowability
  
  European Pharmacopoeia: Flowability File
- Select activity European Pharmacopoeia: Powder Flow
  
  European Pharmacopoeia: Powder Flow File
- Select activity European Pharmacopoeia: Powder flow properties by shear cell methods
  
  European Pharmacopoeia: Powder flow properties by shear cell methods File
- Select activity __________________________________________________... (kopie)
  
  _____________________________________________________________________________
  
  TASKS
- Select activity Task No. 1: Flow properties, lubricants
  
  Task No. 1: Flow properties, lubricants Assignment
- Select activity Task No. 2: Flow properties, microparticles, coated tablets
  
  Task No. 2: Flow properties, microparticles, coated tablets Assignment
Select section DISSOLUTION TESTING

DISSOLUTION TESTING
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  PRACTICAL TRAINING:
- Select activity Dissolution - tablet appearance
  
  Dissolution - tablet appearance Journal
- Select activity Video: Release of model drug from acid-resistant foil
  
  Video: Release of model drug from acid-resistant foil Interactive Content
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  EXAMPLE OF THE PROTOCOL:
- Select activity Protocol: Release of model drug from acid-resistant foil, release of model drug from tablets
  
  Protocol: Release of model drug from acid-resistant foil, release of model drug from tablets File
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  ADDITIONAL MATERIALS:
- Select activity Youtube video: Dissolution apparatus with paddles
  
  Youtube video: Dissolution apparatus with paddles Interactive Content
- Select activity Youtube video: Dissolution testing - How does it work?
  
  Youtube video: Dissolution testing - How does it work? Interactive Content
- Select activity Youtube video: Dissolution devices
  
  Youtube video: Dissolution devices Interactive Content
- Select activity Youtube video: Flow-through cell
  
  Youtube video: Flow-through cell Interactive Content
- Select activity European Pharmacopoeia: Dissolution test for solid dosage forms
  
  European Pharmacopoeia: Dissolution test for solid dosage forms File
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  TASKS
- Select activity Task No. 1: Acid-resistant coating
  
  Task No. 1: Acid-resistant coating Assignment
- Select activity Task No. 2.: Dissolution test
  
  Task No. 2.: Dissolution test Assignment
- Select activity Test: Dissolution testing
  
  Test: Dissolution testing Quiz
  
  The test contains 10 questions. You have 5 minutes to complete it and you need at least 6 correct answers. You have one attempt.
Select section PROPERTIES OF TABLETS

PROPERTIES OF TABLETS
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  PRACTICAL TRAINING:
- Select activity Video: Friability of uncoated tablets
  
  Video: Friability of uncoated tablets Interactive Content
- Select activity Video: The crushing strength of tablets
  
  Video: The crushing strength of tablets Interactive Content
- Select activity Youtube video: Disintegration of tablets
  
  Youtube video: Disintegration of tablets Interactive Content
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  EXAMPLE OF THE PROTOCOL:
- Select activity Protocol: Evaluation of tablets
  
  Protocol: Evaluation of tablets File
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  ADDITIONAL MATERIALS:
- Select activity Youtube video: Semi-Automatic Tablet Testing System (measurement of crushing strenght, weight, tablet dimensions all-in-one)
  
  Youtube video: Semi-Automatic Tablet Testing System (measurement of crushing strenght, weight, tablet dimensions all-in-one) Interactive Content
- Select activity Youtube video: Tablet disintegration
  
  Youtube video: Tablet disintegration Interactive Content
- Select activity European Pharmacopoeia: Tablets
  
  European Pharmacopoeia: Tablets File
- Select activity European Pharmacopoeia: Friability of uncoated tablets
  
  European Pharmacopoeia: Friability of uncoated tablets File
- Select activity European Pharmacopoeia: Disintegration of tablets and capsules
  
  European Pharmacopoeia: Disintegration of tablets and capsules File
- Select activity European Pharmacopoeia: Uniformity of mass of single-dose preparations
  
  European Pharmacopoeia: Uniformity of mass of single-dose preparations File
- Select activity European Pharmacopoeia: Resistance to crushing of tablets
  
  European Pharmacopoeia: Resistance to crushing of tablets File
- Select activity __________________________________________________...
  
  _______________________________________________________________________________
  
  TASKS
- Select activity Tasks: Evaluation of tablets
  
  Tasks: Evaluation of tablets Assignment
- Select activity Test: Tablet properties
  
  Test: Tablet properties Quiz
  
  The test contains 10 questions. You have 5 minutes to complete it and you need at least 6 correct answers. You have one attempt.
Select section RHEOLOGY

RHEOLOGY
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  THEORETICAL BACKGROUND
- Select activity Lecture on rheology_Physical Principles of DF
  
  Lecture on rheology_Physical Principles of DF File
- Select activity Rheology_prezentation of seminar
  
  Rheology_prezentation of seminar File
- Select activity Basic terms
  
  Basic terms File
- Select activity Types of flow_instruction video
  
  Types of flow_instruction video URL
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  PRACTICAL TRAINING
- Select activity Instructions for measurements
  
  Instructions for measurements Folder
- Select activity Measurement on a capillary viscometer_video
  
  Measurement on a capillary viscometer_video Interactive Content
- Select activity Measurement on a spindle rotational viscometer_video
  
  Measurement on a spindle rotational viscometer_video Interactive Content
- Select activity Absolute rotational rheometer_introduction video
  
  Absolute rotational rheometer_introduction video Interactive Content
- Select activity Measurement of consistency by penetrometry_video
  
  Measurement of consistency by penetrometry_video Interactive Content
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  ADDITIONAL MATERIALS
- Select activity Ph.Eur.10.0
  
  Ph.Eur.10.0 Folder
- Select activity Spindle viscometer mesurement-video1
  
  Spindle viscometer mesurement-video1 URL
- Select activity Spindle viscometer measurement-video2
  
  Spindle viscometer measurement-video2 URL
- Select activity __________________________________________________...
  
  _____________________________________________________________________________
  
  TASKS
- Select activity Evaluation of measurements on a capillary viscometer.
  
  Evaluation of measurements on a capillary viscometer. Assignment
- Select activity Test_rheology and rheometry
  
  Test_rheology and rheometry Quiz
  
  The test contains 10 questions. You have 5 minutes to complete it and you need at least 6 correct answers. You have one attempt.
Select section MÁTE DOTAZY?

MÁTE DOTAZY?

Not available

Section outline

INTRODUCTION

PREPARATION AND EVALUATION OF GRANULAR POWDERS

EVALUATION OF FLOW PROPERTIES, PREPARATION OF MICROPARTICLES, SUGAR COATING

DISSOLUTION TESTING

PROPERTIES OF TABLETS

RHEOLOGY

MÁTE DOTAZY?