Section outline

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      STUDY MATERIALS:

    • Theoretical introduction Fichier
    • Rheology-Rheometry_Physical Principles of DF_lecture Fichier
    • Evaluation of spreading properties of semisolid preparations Fichier
    • Tixotropy test Fichier
    • Evaluation of adhesive properties Fichier

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      INSTRUCTIONS:

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      ADDITIONAL MATERIALS:

    • Measurement on Kinexus rheometer URL
    • Determination of pressure sensitive tack and adhesion Fichier
    • Evaluating product spreading characteristics Fichier
    • Three step shear rate - Thixotropy test Fichier

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      REVISION:

      1. Characterize the rheological behavior of semisolid excipients.
      2. What is the yield stress (yield poin)?
      3. What models are used to describe pseudoplastic/plastic flow?
      4. What is the consistency index (coefficient) K and the index of flow behavior n?
      5. What is thixotropy?
      6. What can thixotropy be used in pharmaceutical technology for?
      7. Describe the rheogram of a thixotropic material.
      8. Describe the course of the thixotropic test (Three Step Shear Rate/Thixotropy test).
      9. Describe the course of the adhesive test (Squeeze and pull off test).
      10. What parameters are used to evaluate the adhesive test?